Beilstein J. Nanotechnol.2022,13, 1051–1067, doi:10.3762/bjnano.13.92
Intelligence Education and Research, Hanyang University, Ansan 426-791, South Korea 10.3762/bjnano.13.92 Abstract Biomimetic materials for better bonegraft substitutes are a thrust area of research among researchers and clinicians. Autografts, allografts, and synthetic grafts are often utilized to repair and
tissue engineering applications.
Keywords: antibacterial activity; biomimetic materials; bonegraft substitutes; chitosan; gold; osteoinductive; silver; Introduction
Bone-related defects and diseases are a serious concern to the life of patients [1]. Autografts, allografts, and synthetic grafts are
frequently utilized by clinicians to treat bone defects. Bone grafts should have osteoconductive, osteoinductive, and osteogenic properties to mimic the natural function of the bone [2]. Autografts are considered the gold-standard bonegraft substitute since it has all three properties previously mentioned
Beilstein J. Nanotechnol.2016,7, 1794–1799, doi:10.3762/bjnano.7.172
diameter ≈800 μm) and were found to possess compressive strengths from 0.45 to 1.0 MPa. This new approach can be effectively applied for fabrication of biocompatible scaffolds for bone tissue engineering constructions.
Keywords: 3D printing; bonegraft; calcium phosphate; composite materials; sodium
popular biomaterial because of a number of key advantages: convenient precursors, nontoxic, excellent biocompatibility and appropriate biodegradability [5][6][7]. Additionally, CPs are widely used for bonegraft substitution due to their chemical affinity to the bone mineral content [8]. One of the